Fiware is an Open Source platform and Orion is its broker component that handles NGSI entities and subscriptions.
Orion is heavily used inside the PIXEL europen project and widely used to collect data from IoT and so on.
python-orion-client is a Fiware Orion API Python client implementation. It comes along with helpers to handle NGSI datamodels.
The goal is not to cover 100% of the API, just all the basics.
Soon to be pulished at Github.